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Research indicates that certain groups should avoid or use melatonin with caution:

  • Pregnant or breastfeeding women: Due to limited safety data
  • People with autoimmune disorders: May stimulate immune system activity
  • Those with bleeding disorders: Can increase bleeding risk
  • People with depression: May worsen symptoms

Studies show melatonin can interact with various medications, including blood pressure medications, diabetes drugs, and immunosuppressants. Always consult healthcare providers before starting melatonin, especially if you have existing medical conditions or take prescription medications.

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Last Updated: October 13, 2025

Disclaimer: This information is for educational purposes only and should not replace professional medical advice. Always consult with a healthcare provider before making health decisions.

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