Table of Contents

Research indicates that certain groups should avoid or use melatonin with caution:

  • Pregnant or breastfeeding women: Due to limited safety data
  • People with autoimmune disorders: May affect immune system function
  • Those with bleeding disorders: Can interact with blood thinners
  • People with depression: May affect mood regulation

Studies show melatonin can also interact with various medications, including:

  • Blood pressure medications
  • Diabetes medicines
  • Birth control pills
  • Immunosuppressants

Always consult a healthcare provider before starting melatonin, especially if you have any chronic conditions or take regular medications.

About the Author

✓ Expert Reviewed: This content has been reviewed by qualified professionals in the field.

Last Updated: October 5, 2025

Disclaimer: This information is for educational purposes only and should not replace professional medical advice. Always consult with a healthcare provider before making health decisions.

Editorial Standards: Our Medical Content StandardsThe Health Research Team is a collaborative network of healthcare professionals, graduate researchers, and medical science students dedicated to synthesizing peer-reviewed health research for public education. Our interdisciplinary approach combines expertise from nutrition science, physiotherapy, nursing, and medical research to provide comprehensive, evidence-based health information.Click to read our Editorial Policy in details - Medical Oversight: All health information is overseen by board-certified physicians and follows FDA guidelines for health content