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Medical research indicates that certain groups should avoid or use melatonin with caution:

  • Pregnant or breastfeeding women due to limited safety data
  • People with autoimmune disorders
  • Those with bleeding disorders or taking blood thinners
  • People with depression or other psychiatric conditions
  • Individuals with diabetes or high blood pressure

Additionally, melatonin can interact with various medications, including:

  • Blood pressure medications
  • Diabetes medications
  • Immunosuppressants
  • Anticoagulants

Always consult a healthcare provider before starting melatonin, especially if you have underlying health conditions or take other medications.

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Last Updated: October 1, 2025

Disclaimer: This information is for educational purposes only and should not replace professional medical advice. Always consult with a healthcare provider before making health decisions.

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