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Melatonin is a hormone naturally produced by the pineal gland in your brain that helps regulate your sleep-wake cycle (circadian rhythm). According to research, melatonin levels typically rise in the evening and fall in the morning, signaling to your body when it’s time to sleep and wake up.

The hormone works by:

  • Binding to receptors in your brain that reduce nerve activity
  • Reducing dopamine levels, which helps you stay awake
  • Regulating your body temperature for optimal sleep

When taken as a supplement, synthetic melatonin mimics the effects of your natural melatonin to help establish healthy sleep patterns.

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Last Updated: October 11, 2025

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