Melatonin is a natural hormone produced by the pineal gland in the brain that helps regulate our sleep-wake cycle (circadian rhythm). According to research, melatonin levels naturally rise in the evening and fall in the morning, signaling to our body when it’s time to sleep and wake up.
The hormone works by:
- Binding to receptors in the brain that reduce nerve activity
- Decreasing dopamine levels that keep us alert
- Regulating the circadian rhythm
- Reducing body temperature
When taken as a supplement, synthetic melatonin mimics the effects of our natural melatonin to help promote sleep. Studies show it’s particularly effective for treating jet lag and delayed sleep phase syndrome.
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Last Updated: September 3, 2025
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