The main symptoms of COPD include persistent cough, mucus production, shortness of breath (especially during physical activity), wheezing, and chest tightness. As the disease progresses, individuals may experience fatigue, weight loss, and frequent respiratory infections. Symptoms typically worsen over time and can significantly impact daily activities and quality of life. However, it’s important to note that some individuals may not experience noticeable symptoms until the disease is in its later stages, which highlights the importance of early detection and management. A study published in the Annals of the American Thoracic Society found that early recognition and treatment of COPD can improve lung function and reduce exacerbations.