While melatonin is generally considered safe for short-term use, studies show it can cause several side effects:
- Headaches and dizziness
- Daytime sleepiness
- Mild anxiety or irritability
- Short-term feelings of depression
- Nausea
- Changes in blood pressure
Less common side effects include vivid dreams or nightmares, and temporary changes in blood sugar levels. Long-term effects are still being studied. People taking certain medications, pregnant women, and those with autoimmune conditions should consult healthcare providers before using melatonin.
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Last Updated: August 24, 2025
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