While melatonin is generally considered safe for short-term use, research indicates several possible side effects:
- Common side effects:
- Headache
- Dizziness
- Daytime sleepiness
- Short-term feelings of depression
- Less common side effects:
- Mild anxiety
- Temporary changes in blood pressure
- Vivid dreams or nightmares
Long-term effects are still being studied. Melatonin may interact with certain medications, including blood thinners and diabetes medications. It’s important to consult with a healthcare provider before starting supplementation, especially if you have existing medical conditions.
✓ Expert Reviewed: This content has been reviewed by qualified professionals in the field.
Last Updated: August 14, 2025
Disclaimer: This information is for educational purposes only and should not replace professional medical advice. Always consult with a healthcare provider before making health decisions.
Editorial Standards: Our Medical Content StandardsThe Health Research Team is a collaborative network of healthcare professionals, graduate researchers, and medical science students dedicated to synthesizing peer-reviewed health research for public education. Our interdisciplinary approach combines expertise from nutrition science, physiotherapy, nursing, and medical research to provide comprehensive, evidence-based health information.Click to read our Editorial Policy in details - Medical Oversight: All health information is overseen by board-certified physicians and follows FDA guidelines for health content