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While melatonin is generally considered safe for short-term use, studies indicate several possible side effects:

  • Daytime drowsiness
  • Headaches
  • Dizziness
  • Mild anxiety
  • Short-term feelings of depression
  • Mild tremors
  • Mild nausea

Less common but more serious side effects can include:

  • Vivid dreams or nightmares
  • Reduced blood pressure
  • Interactions with blood thinners and diabetes medications

Important note: Long-term effects of regular melatonin use are still being studied. Research suggests that prolonged use might affect natural hormone production and should be discussed with a healthcare provider.

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Last Updated: August 12, 2025

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