The onset time for melatonin varies among individuals, but research indicates that it typically takes 30-60 minutes to start working. Factors affecting onset include:
- Dosage form (liquid typically works faster than tablets)
- Individual metabolism
- Whether taken with food
- Current sleep-wake cycle
For optimal results, take melatonin 30-60 minutes before your intended bedtime. Studies show that consistent timing is crucial for effectiveness. The supplement’s effects typically last 4-8 hours, though this can vary based on dosage and individual factors.
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Last Updated: September 13, 2025
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