Melatonin typically begins working within 30-60 minutes after ingestion. Research shows that the timing of intake is crucial for effectiveness. For optimal results:
- Take 30-60 minutes before desired sleep time
- Maintain a consistent dosing schedule
- Avoid exposure to bright light after taking
The duration of effect varies by formulation: immediate-release forms last 4-5 hours, while extended-release versions can last 6-8 hours. Studies indicate that individual response times can vary based on metabolism, age, and other factors.
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Last Updated: September 11, 2025
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