A structured preventive nursing program reduced falls by 64% among older adults with non-Hodgkin's lymphoma undergoing chemotherapy, decreasing fall incidence from 19.8% to 7.1% compared to standard care.
- Targeted nursing intervention cut fall rates from 19.8% to 7.1% in older cancer patients on chemotherapy
- Patients receiving preventive care had fewer severe injuries and better treatment adherence
- Study enrolled 210 patients aged 65+ with non-Hodgkin's lymphoma across 12 weeks
How this compares to prior research
Non-Hodgkin\’s lymphoma predominantly affects older adults, and chemotherapy remains the primary treatment for many subtypes. Prior research established that chemotherapy-related side effects such as myelosuppression, anemia, and neuropathy contribute to heightened fall risk in older patients. Falls in this population were known to cause serious complications including fractures and intracranial injuries, potentially delaying oncological treatment, but structured prevention protocols had not been rigorously tested.
Fall prevalence trends in older adults, global data, 1980–1989
Key findings
- Fall incidence was 7.1% in the intervention group versus 19.8% in standard care group over 12 weeks
- Patients receiving preventive nursing had improved functional mobility measured by Timed Up and Go tests
- Intervention group showed better chemotherapy adherence and higher quality of life scores
What this means in practice
- Ask your oncology team about fall risk assessment if you\’re 65+ and starting chemotherapy for lymphoma
- Consider requesting individualized fall prevention measures as part of your cancer care plan
- Report balance problems or weakness immediately to prevent treatment delays from fall injuries
Frequently asked questions
Why do older adults with lymphoma have higher fall risk during chemotherapy?
Chemotherapy causes side effects including myelosuppression, anemia, and neuropathy, all of which increase fall risk. These effects are particularly pronounced in older patients aged 65 and above.
What did the preventive nursing program include?
The program was a multifaceted intervention based on individualized risk assessment, though specific components are not detailed in the abstract. It was compared against standard oncology nursing care.
How serious are falls in older cancer patients?
Falls can cause fractures and intracranial injuries, impact functional status, and potentially delay cancer treatment. This study found fewer severe injuries in the intervention group.
Key terms explained
Non-Hodgkin's lymphoma
A diverse group of blood cancers affecting the lymphatic system, most common in older adults
Myelosuppression
Decreased bone marrow activity reducing blood cell production, a common chemotherapy side effect
Timed Up and Go test
A clinical assessment measuring time to stand, walk, turn, and sit to evaluate mobility and fall risk
Source: A clinical study on fall risk assessment and preventive nursing in older adults with non-Hodgkin's lymphoma undergoing chemotherapy-a randomized controlled trial. · DOI: pii: 775. doi: 10.1007/s00520-026-10989-0