Pain is the symptom !
Efgartigimod and IVIg both achieved ~90% remission rates in patients with impending myasthenic crisis Efgartigimod worked 4 days faster (8 days vs 12 days median time to remission) Both treatments showed similar safety profiles with minimal progression to full crisis
Read MoreOral paclitaxel (DHP107) achieved 25% response rate compared to 28.6% for IV paclitaxel Median progression-free survival was 5.5 months for oral vs 4.7 months for IV Side effect profiles differed: oral form caused more GI symptoms, IV caused more neuropathy and hair loss
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DNA280 immunoadsorption plus standard therapy ranked favorably for improving lupus disease activity scores DNA280 combined with plasma exchange significantly reduced 24-hour proteinuria versus standard treatment alone Evidence quality was limited by study heterogeneity and reliance on surrogate outcomes
Read MorePlacebo with positive expectations reversed heightened pain and autonomic responses caused by experimental sensitization Control group without placebo conditioning maintained elevated pain and skin conductance levels Pain ratings and autonomic responses decreased independently, suggesting different modulatory pathways
Read MoreReview of 358 pediatric brain tumor patients treated with stereotactic radiosurgery found one-year survival rates between 85-100% Local tumor control varied widely (29-100%) depending on tumor type and whether treatment was for new or recurrent disease Most common side effects included temporary swelling and tissue damage, especially in previously treated patients or tumors near critical brain structures
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